Ike witnesses a robbery and murders and he's the only witness. Now the man with his life on the line wants to end Ike's before the trial. Can the other riders keep everyone alive until the end of the trial?
Kid's long lost brother is in Sweetwater and while they think he's an Army Officer, he's biding his time until his gang can steal a shipment. He leaves a lasting impression on all at the Express Station.
A Pony Express Station is attacked by Indians and Kid captures a young half-blood brave called Curly. Believing him responsible for the attack he brings him to Sweetwater for trial, but Lou and Jimmy find the real culprits.
Jimmy draws the short lot and has to go with Emma to Fort Reunion. They end up riding into a tense situation as the US Army is in the middle of conflict with a local tribe. Sam and Buck ride after them to help while the others have to survive with Teaspoon as a cook.
After an old friend of Teaspoon's dies at the Saloon, Jimmy shocks his fellow riders by taking a job there. While the riders struggle to understand Jimmy's sudden change in attitude he's trying to stop his new boss from stealing Army artillery.
Cody and Kid visit in town that hides a dark secret. Unfairly accused of cheating, Kid’s condemned to work in a mine run by the corrupted mayor of the town. When Cody returns to Sweetwater without him, their friends and Sam come to his rescue.
While on a run, Lou buys a dress and enjoys a nice evening, with an older but charming, Tyler DeWitt. He comes to Sweetwater looking for her, his charm slipping to reveal a violent attitude toward women. What makes matters worse is that he’s behind a series of robberies.
Emma is dismayed when her estranged husband returns, seeking shelter. To everyone's surprise, Emma agrees that he can stay, but her insistence on defending his increasingly odd behavior strains her relationship with Sam.
Cody's not-so-secret mission to deliver a Government message finds him pursued by double agents, and crossing paths with a pet grizzly and an eccentric widow. Meanwhile with Emma away and Lou on a run, a baby is left at the way station.
Kathleen Devlin is a headstrong young woman determined to push her father's buttons. What better way to do it than to spend time with Buck. Buck's heart may not be the only casualty when this relationship ends badly.
The hero worship of a bookish college boy tries Hickok's patience, and it doesn't help that the determined lad's employer has him working on a plan that will send the riders into dangerous new territory.
Hickok's former friend and rival brings news that the daughter of their gunfighting mentor has been kidnapped. Hickok joins the search, unaware that the young woman actually fled with proof of her father's crooked ways.
A regretful Sam recalls hunting his wife's murderers, but his thirst for vengeance is renewed when the remaining killer shows up as a wealthy businessman who announces that Sweetwater has a new marshal.
With the anniversary of the massacre approaching, Teaspoon and a fellow ex-Ranger travel to warn their old team that someone is murdering those who survived the Alamo. Concerned, Buck and Hickok defy Teaspoon's orders not to follow.
As the Army occupies Sweetwater, Kid joins a group of Southern sympathizers whose raids ignite divided opinions among the townspeople. Meanwhile, Jimmy attends class at the schoolhouse, and Ike takes a shine to a jilted mail-order bride.